Medlines

Friday, October 23, 2026 In today's episode, Dr. Alok Patel (@alokpatelmd) & Adam Rose (@adjoro) cover a phase three trial of nicotinamide riboside in early Parkinson disease. Over 52 weeks, the supplement boosted NAD metabolism but showed no clinical benefit, raising questions for NAD boosting strategies. They also walk through a large hospital comparison of phenobarbital and diazepam for alcohol withdrawal, with similar stays and ventilation rates and fewer self directed discharges on phenobarbital, and why diazepam protocols may stay the course pending randomized trials. Plus: they also discuss national measles trends, FDA warning letters to Amazon and Walmart, and more. Coverage Timeline: (00:00) Intro (01:05) NR Supplement Trial for Parkinson's (03:01) NAD Supplements & Influencer Hype (04:49) Phenobarbital vs. Diazepam (07:30) Measles Surge in US (08:27) New Sunscreen Ingredient BEMT (09:01) Blood Clots Have a story, think we missed something, want to say hi, or curious to learn about the Medlines…

Friday, October 16, 2026 In today's episode, Dr. Alok Patel (@alokpatelmd) & Eva Johnson cover the FDA clearance of Motivista as the first prescription app for negative symptoms of schizophrenia. They break down the 16 week CONVOKE trial and what a 2.6 point edge over a control app means for stable patients on antipsychotics. They also review new ACP guidance placing menopausal hormone therapy first for hot flashes and night sweats, with second and third line options. Plus: they discuss early feasibility data on a medical AI chatbot for pre visit histories, new federal recommendations on concentrated kratom products, and more. Coverage Timeline: (00:00) Intro (01:08) Schizophrenia App Cleared (03:50) Hot Flashes Guidance (04:47) Dogs & Sleep Study (06:51) AI In Urgent Care (08:37) Awards & Dahlias Have a story, think we missed something, want to say hi, or curious to learn about the Medlines team? Visit www.medlinespod.com or email medlines@human-content.com. Sources & Media Attributions for Today's Episode…

Friday, October 9, 2026 In today's episode, Dr. Will Flanary (@drglaucomflecken) & Adam Rose (@adjoro) cover Phase 3 results for retatrutide with up to 28.3% average weight loss at 80 weeks. They explain dosing, tolerability and what remains unproven for heart and kidney outcomes and how retatrutide compares with current GLP-1 options. They also break down a federal proposal to modernize airline emergency kits around nine life threatening categories with airline level discretion. Plus: they discuss a growing pediatric heart valve, the return of Doc, Best Medicine, Chicago Med and Grey’s Anatomy, and more. Coverage Timeline: (00:00) Intro (00:50) Retatrutide Weight Loss Trial (03:27) FAA Airline Medical Kits (06:56) Growing Heart Valve (07:26) Fasting Before Blood Work (08:18) Medical Drama Premieres Have a story, think we missed something, want to say hi, or curious to learn about the Medlines team? Visit https://www.medlinespod.com or email medlines@human-content.com. Sources & Media Attributions for…

Friday, October 2, 2026 In today's episode, Dr. Jennifer Lincoln (@drjenniferlincoln) joins Medlines as a new anchor! She and Eva Johnson cover an FDA advisory panel vote on an early cancer detection blood test for adults 50 and older. The panel called the test safe, then split on whether it works. The agency still has to rule. They also walk through a UCSF comparison of myomectomy and radiofrequency ablation for uterine fibroids. Both treatments improved symptoms over two years, and neither difference reached the study threshold for a clinically important advantage. Plus: new findings on animal therapy, and more. Coverage Timeline: (00:00) Intro (02:01) FDA Backs Multi-Cancer Blood Test (05:08) Uterine Fibroids: Surgery vs. Heat Therapy (07:47) Gambling ER Visits Surge (09:01) Miniature Horses Lift Teen Mood Have a story, think we missed something, want to say hi, or curious to learn about the Medlines team? Visit www.medlinespod.com or email medlines@human-content.com. Sources & Media Attributions for…

Friday, September 25, 2026 In today's episode, Dr. Will Flanary (@drglaucomflecken) & Adam Rose (@Adjoro) cover new research on colonoscopy surveillance after high risk adenomas. A large randomized trial found that waiting five years instead of three led to nearly identical colorectal cancer rates. They explain what the interim results mean for screening guidance and what remains unanswered. Then they turn to a Washington court ruling on whether raw audio from an AI scribe counts as part of the medical record. Plus: they discuss Nathan Fielder’s documentary on Theranos founder Elizabeth Holmes, prenatal diet and food allergy risk, and more. Coverage Timeline: (0:00) Intro (0:54) Colonoscopy Intervals (3:55) AI Scribe Ruling (7:25) Theranos Doc (9:07) Conjoined Twins Have a story, think we missed something, want to say hi, or curious to learn about the Medlines team? Visit www.medlinespod.com or email medlines@human-content.com. Sources & Media Attributions for Today's Episode Available At:…

Friday, September 18, 2026 In today's episode, Dr. Alok Patel (@AlokPatelMD) & Eva Johnson cover new migraine prevention guidelines that put CGRP targeted therapies up front as first line options without requiring older drugs first. They explain who qualifies at four or more headache days per month, how to assess response after 8 to 12 weeks, and safety notes for pregnancy. They also break down The Pitt's second Emmy run, with 25 nominations and back to back wins for Noah Wyle and Outstanding Drama. Plus: rising rabies exposures, an MRSA outbreak tied to bouncy castles, and more. Coverage Timeline: (00:00) Intro (01:08) New Migraine Guidelines (04:15) The Pitt Sweeps Emmys (08:22) Rabies on the Rise (09:22) MRSA from Bouncy Castles Have a story, think we missed something, want to say hi, or curious to learn about the Medlines team? Visit www.medlinespod.com or email medlines@human-content.com. Sources & Media Attributions for Today's Episode Available At: www.medlinespod.com/sources Medlines is a Human…

Friday, September 11, 2026 In today's episode, Dr. Alok Patel (@AlokPatelMD) & Adam Rose (@Adjoro) cover a record pig kidney bridge that kept a New Hampshire man off dialysis for 271 days with no sign of rejection and without blocking his next human transplant. They break down the 69 edits behind the eGenesis organ and why The Lancet case matters for over 100,000 Americans waiting for a kidney. They also dig into new UK and US surveys showing most emergency staff face violence and what leaders say must change. Plus: a sharp rise in GLP-1 prescriptions for young children, fake weight loss drugs tied to liver injury, and more. Coverage Timeline: (00:00) Intro (01:03) The Pig Kidney Record (03:59) Violence in the Hospital (08:57) Brain Aneurysm Detection Rates (09:26) Teen Illicit Drug Use Trends Have a story, think we missed something, want to say hi, or curious to learn about the Medlines team? Visit www.medlinespod.com or email medlines@human-content.com. Sources & Media Attributions for Today's Episode…

Friday, September 4, 2026 In today's episode, Dr. Will Flanary (@drglaucomflecken) & Eva Johnson cover the FDA authorization of Aletta, the first standalone robot that draws blood without hands on operator intervention. The Vitestro system uses near infrared light and Doppler ultrasound to find veins, and one phlebotomist can supervise three units at a 94.5 percent first stick rate. They also break down a trial of atorvastatin in nearly 10,000 healthy adults over 70, where a 30 percent relative reduction in cardiovascular events came with no significant gain in disability free survival. Plus: new FDA decisions on skin and tobacco products, teen safety updates from Meta, and more. Coverage Timeline: (00:00) Intro (01:00) Aletta: Autonomous Blood Draw Robot (04:23) Statins for Healthy Older Adults (07:19) Lysria for Dermatomyositis (09:16) Ebola Vaccination & Slow Running Have a story, think we missed something, want to say hi, or curious to learn about the Medlines team? Visit www.medlinespod.com or email…

Friday, August 28, 2026 In today's episode, Alok Patel (@AlokPatelMD) & Adam Rose (@Adjoro) cover Epic bringing prior authorization checks directly into the EHR. New federal rules will require Medicare Advantage Medicaid and ACA marketplace insurers to support electronic prior authorization APIs by January 1. Epic's Coverage Requirements Discovery shows coverage requirements and documentation needs inside the chart without payer portals or phone calls. They also break down undisclosed deaths in Chinese gene editing trials involving high dose AAV9 vectors and what the delays reveal about safety oversight. Plus: they discuss the Oura sleep tracking lawsuit and new real world psilocybin data from Oregon and more. Coverage Timeline: (00:00) Intro (01:03) Electronic Prior Auth (03:41) Gene Editing Deaths (06:41) Measles Outbreak (07:23) MyChart Phishing Scam (08:05) Mediterranean Diet (08:47) Legal Psilocybin Have a story, think we missed something, want to say hi, or curious to learn about the Medlines team?…

Friday, August 21, 2026 In today's episode, Dr. Will Flanary (@drglaucomflecken) & Eva Johnson cover a historic drop in prescription drug prices. Prices fell 3.1% over the past year, the steepest annual decline since 1963, and the anchors unpack what is actually driving it from generics to GLP-1 competition to the Inflation Reduction Act. They also break down why the national index does not always match what patients pay at the pharmacy counter. Plus: a split between two studies on whether CTE can be diagnosed in living patients, and more. Coverage Timeline: (00:00) Intro (01:04) Drug Prices Drop (04:25) Diagnosing CTE in Living Patients (08:18) Waist Size vs BMI (09:26) C. Diff Treatment Updates Have a story, think we missed something, want to say hi, or curious to learn about the Medlines team? Visit https://www.medlinespod.com or email medlines@human-content.com. Sources & Media Attributions for Today's Episode Available At: www.medlinespod.com/sources Medlines is a Human Content Production

Friday, August 14, 2026 In today's episode, Adam Rose (@adjoro) & Dr. Alok Patel (@alokpatelmd) cover the FDA's landmark approval of Moderna's first mRNA flu vaccine for adults. They break down the phase-three trial showing the mRNA shot produced fewer confirmed influenza cases than standard vaccines, and what a complicated insurance landscape means for access this flu season. Plus: researchers at the Arc Institute fed millions of viral DNA sequences to a language model. It wrote new genomes that had never existed in nature, and sixteen of them came to life in the lab. Then, they look at a new narcolepsy drug targeting the underlying orexin deficiency, a Salmonella outbreak linked to jalapeños spreading through 27 states, and over 2,400 measles cases putting U.S. elimination status in jeopardy. Coverage Timeline: (0:00) Intro (1:01) First mRNA Flu Vaccine Approved (4:52) AI Designs Functional Viruses (8:54) Salmonella Jalapeño Outbreak (9:44) Measles Resurgence (10:04) Women's Pro Baseball Have a story,…

August 7, 2026 In today's episode, Dr. Will Flanary (@DrGlaucomflecken) & Eva Johnson cover the American Red Cross declaring its second-ever national blood crisis, with Type O blood critically low and hospitals postponing transfusions. They break down what's driving the shortage and debate whether blood donors deserve HOV-lane perks. Then: a 36-year-old Iowa woman with cystic fibrosis becomes the first known U.S. patient to receive a quadruple organ transplant involving re-transplanted lungs, in addition to a liver and kidney, at Northwestern Medicine. Plus: Florida advises caution on psychiatric medication for children, a promising non-opioid pain drug (LTG-001) reduces opioid use after surgery, and Will reveals whether he actually knows his blood type. Coverage Timeline: (0:00) Intro & Trivia Question (1:00) Red Cross Blood Crisis (3:54) Should We Pay Blood Donors? (4:44) Historic 4-Organ Transplant (8:32) Florida Psych Meds Debate (10:04) Non-Opioid Pain Relief Trial Have a story, think we missed…

Friday, July 31, 2026 In today's episode, Dr. Alok Patel (@alokpatelmd) & Adam Rose (@adjoro) cover a Florida man's lawsuit against OpenAI after ChatGPT repeatedly dismissed his pulmonary embolism symptoms as "not something dangerous." The case raises urgent questions about AI medical liability just as a new JAMA analysis reveals updated cholesterol guidelines now make 87.5 million US adults eligible for statins (more than 56% of the 30-to-79 population). Plus: they also discuss the FDA's first dual-ingredient OTC pain reliever, Lego MRI models cutting pediatric sedation rates by nearly half, and Europe's approval of a retinal implant that helped 84% of participants read again. Plus: oral GLP-1 competition heats up and a new smell-impairment and depression link. (00:00) Intro & Trivia Question (01:05) AI Medical Advice Lawsuit (OpenAI/ChatGPT) (04:34) New Cholesterol Guidelines & Statin Eligibility (07:05) Off The Clock GLP-1s, Lego MRI, OTC Pain Combo (11:03) Trivia Answer Have a story, think we missed…

Friday, July 24, 2026 In today's episode, Dr. Alok Patel (@alokpatelmd) & Eva Johnson cover CMS's sweeping 2027 physician fee schedule proposal, which would accelerate Medicare's shift from fee-for-service toward value-based, preventive care. They also unpack Kalshi's launch of clinical trial prediction markets; betting on FDA approvals is now a real thing, and the ethical questions are piling up. Coffee gets a heart health endorsement from the AHA, and an outbreak of Legionnaires' disease hits Manhattan's Upper East Side. Last, but far from least, we discuss the FDA's transparency whiplash on rejection letters, the first RCT of a ketogenic diet for severe mental illness, and more. Coverage Timeline: (00:00) Intro & Trivia Question (01:17) Medicare Physician Payment Overhaul (04:30) Prediction Markets for Clinical Trials (07:12) Off the Clock: FDA, Coffee, Outbreak, Ketogenic Diet (09:57) Trivia Answer (11:07) Outro & Disclaimers Have a story, think we missed something, want to say hi, or curious to learn…

Friday, July 17, 2026 In today’s episode, Dr. Will Flanary / Dr. Glaucomflecken (@drglaucomflecken) and Adam Rose cover the EPCAT III trial, which found that aspirin alone was non-inferior to an initial course of rivaroxaban followed by aspirin for preventing major blood clots after elective hip or knee replacement in predominantly standard-risk patients. They examine NICE’s draft recommendation allowing two rapid endometriosis tests, EndoSure and Endotest, to enter limited NHS use while researchers gather additional real-world evidence. Plus: They discuss a recall involving more than 2.5 million bottles of prednisolone acetate eye drops, the first HAVANA Act compensation payments, the expanding Cyclospora response, and The Pitt leading the 2026 Emmy nominations with 25 nods. Coverage Timeline: (00:00) Intro (01:07) Aspirin vs. Rivaroxaban After Joint Replacement (03:19) NICE Endorses Rapid Endometriosis Tests (05:30) FDA Recall of Prednisolone Eye Drops (06:07) First Havana Syndrome Payments (06:41)…

Friday, July 10, 2026 In today's episode, Dr. Will Flanary / Dr. Glaucomflecken (@drglaucomflecken) & Eva Johnson cover the retraction of the Advocate trial after FDA reviewers found the avacopan (Tavneos) dataset was unblinded, re-adjudicated, and altered before being relocked, throwing its approval for ANCA-associated vasculitis into doubt. They break down Medicare's new GLP-1 Bridge program, which offers eligible Part D beneficiaries drugs like Wegovy and Zepbound at $50 a month through the end of 2027, and why that copay sits outside normal Part D accounting. They also track a Cyclospora outbreak now reported across 18 states and why routine washing does not reliably kill it. Plus: they also discuss Alibaba's $600 million fentanyl-precursor settlement, the WHO's first emergency-use Ebola (Bundibugyo) diagnostic, France's deadly heat wave, and more. Coverage Timeline: (00:00) Intro(01:04) Vasculitis Trial Retracted:(03:44) Medicare’s GLP‑1 Bridge(06:02) Parasite, Ebola, Heat Wave Have a story, think we…

Friday, July 3, 2026 In today's inaugural episode, Dr. Will Flanary / Dr. Glaucomflecken (@drglaucomflecken) & Dr. Alok Patel (@alokpatelmd) cover a sharp drop in ACA marketplace enrollment after enhanced tax credits expired, from 24.2 million enrollees in 2025 to roughly 19.2 million in 2026 (a loss of 5 million Americans' health coverage). India is rationing two cornerstone chemotherapy drugs, cisplatin and carboplatin, after supply disruptions tied to rising platinum costs and capped essential medicine prices. A new Annals of Internal Medicine study finds older adults who received a shingles vaccine had a 24 percent lower relative risk of dementia diagnosis. Plus: heat linked to rising suicide rates in young people, the return of the 988 LGBTQ+ crisis line, and a phase 3 trial of infigratinib for achondroplasia. Coverage Timeline: (00:00) Medlines begins! (01:44) ACA enrollment drops as credits expire (03:42) India rations cisplatin & carboplatin (06:03) Shingles vaccine & dementia risk (06:38) Climate,…

Struggling to stay on top of healthcare news because, well, you're too busy working in it? If only there were a way to catch up on things in less time than it takes to get prior auth approved. (Spoiler: There is.) Kick off your Fridays with Dr. Will Flanary (aka Dr. Glaucomflecken), Dr. Alok Patel, Adam Rose, and Eva Johnson as they bring you the week’s most important headlines across clinical care, health policy, publications, medical pop culture, and more. Presented with clear, unbiased, fact-first reporting made strictly for healthcare professionals, by healthcare professionals. Subscribe for new episodes every Friday wherever you get your podcasts (or watch on YouTube. Medicine moves fast... So do we! Want to learn about the Medlines mission? Visit www.medlinespod.com or email medlines@human-content.com. Medlines is a Human Content Production